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Acitrom®

Is a coumarin derivative and functions as vitamin K antagonist. Vitamin K antagonists produce their anticoagulant effect by inhibition of the vitamin K-epoxide-reductase.4-6

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How Does Acitrom® Act?

    Acitrom®

  • Is structurally similar to vitamin K4-6
  • Competitively inhibits the enzyme vitamin K-epoxide reductase4-6
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Indications for Use of Acitrom®

Acitrom® in
DVT & PVD

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Acitrom® in MI,
Post-CABG, HF, AF...

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Acitrom® in Cerebrovascular Diseases

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Acenocoumarol Vs. Warfarin

Acitrom® (Acenocoumarol) is twice as potent as warfarin.

  1. Acitrom® Offers More Stable INR2

    The mean percentage of INR-s in the therapeutic range of 2-3 was 49 ± 22.6% for warfarin and 56 ± 26.8% for acenocoumarol (p < 0.05).

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  2. Acitrom® Provides Superior Anticoagulant Effect7,8

    Acenocoumarol has a rapid onset of action, and the effect is maintained for 15–20 hours. Such properties offer great advantages to its clinical use.

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  3. Acitrom® Has Shorter Half-Life4,9

    Good maintenance of prothrombin time over 24 hours yet rapid reversal of anticoagulant action if needed.
     

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