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  • Indications
  • Post-CABG patients

Acenocoumarol After CABG

Clinical studies have investigated the role of oral anticoagulants including acenocoumarol in preventing occlusion of the venous grafts in patients who have undergone a coronary artery bypass grafting (CABG). These studies have shown that the oral anticoagulants including acenocoumarol are effective in preventing reocclusion of the graft.

Studies in post-CABG patients
Investigators & study design Patients Drug treatment Results
Mulder et al.58
CABADAS study*
Prospective, randomized multicentre study
127 patients who have undergone CABG with venous grafts
  • Aspirin
  • Aspirin + dipyridamole
  • Oral anticoagulants (acenocoumarol or phenprocoumon)
All were given for a period of 1 year
  • No significant difference was observed in the incidence of graft occlusion among the three treatment groups
  • No differences in symptoms of angina or exercise capacity was seen between the treatment groups

*Prevention of Coronary Artery Bypass graft occlusion by Aspirin, Dipyridamole and Acenocoumarol/Phenprocoumon Study